Beaphar Fresh Breath Spray has been specifically formulated to be effective without brushing. Perfect for cats and dogs that aren't used to having their teeth brushed. Beaphar Fresh Breath Spray contains three enzymes that fight bacteria and break down plaque. Protease destroys the protein structure of plaque before it binds with calcium to create tartar. Glucoamylase breaks carbohydrates down into glucose, and glucose oxidase then breaks glucose down into gluconic acid. This is harmless and produces a small amount of hydrogen peroxide, which provides an antibacterial action and kills the bacteria responsible for bad breath. It is important to not use human tooth care products on your pet as these products usually contain fluoride which is toxic to animals and can result in serious health problems. In addition, human toothpaste contains a foaming agent, which if swallowed will irritate your pet's stomach. Beaphar Fresh Breath Spray is fluoride-free and readily accepted by pets.